Nicknamed "The Grand Snicker" on the Hoot Owls, Blanc became well known for his comedy, as well as his skills as a storyteller, ad-libber, musician, vocalist, and, later, orchestra pit conductor. One of his favorite instruments was the sousaphone.
Mel Blanc left KGW in 1932 and moved to Hollywood where success eluded him. In 1933, Blanc returned to Portland to perform on KGW’s sister station KEX in the popular "Cobwebs and Nuts" program. In 1935, Blanc moved to Hollywood again to Warner Brothers’ station KFWB. Blanc did the voices for his first Warner Brothers cartoon in 1937, "Picador Porky." While working on animated cartoons at Warner Brothers studios in Southern California, he became known as the most famous voice actor in American cinema.
During his early years in Portland radio, Blanc laid the foundation for many of his later cartoon voices and comedy routines. While reflecting later in life, Mel Blanc recognized Vaudeville as a big influence in his life. He passed away in 1989.